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3:52
YouTube
Universal Lens
Why Tumor MHC-II Matters: Unlocking CD4+ T-Cell Immunity for Better Cancer Immunotherapy
Explore how tumor-expressed MHC-II (tsMHC-II) shapes the immune response and why it could predict immunotherapy outcomes. We break down how tsMHC-II is regulated by MAPK and NF-κB signaling, the role of CIITA, and the impact of IFN-γ on activating CD4+ T cells. Learn how multi-omics analyses reveal heterogeneity across cancers and why tsMHC ...
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