McConnell’s sign is defined as right ventricular free wall akinesis with sparing of the apex. Typically this looks as if the apex of the RV is a trampoline bouncing up and down while the rest of the RV remains still. This finding is not sensitive, but in a small study was specific for an acute PE. Other causes of acute right ventricular ...

Oct 7, 2008 · McConnell’s sign is a distinct echocardiographic finding described in patients with acute PE. There is a distinct regional pattern of right ventricular dysfunction, with akinesia of the mid free wall (centerline excursion, −0.2±0.8 mm; P=0.0001 versus normal) but normal motion at the apex (centerline excursion, 5.7±0.8 mm; P=NS versus normal). 1 Three mechanisms have …

Nov 21, 2022 · The McConnell's sign describes a regional pattern of acute right ventricular dysfunction on transthoracic echocardiography first observed in a cohort of patients with acute pulmonary thromboembolism.In contrast to the global wall motion abnormalities observed in chronic right ventricular dysfunction, this sign refers to the coexistence of akinesia of the mid …

McConnell's sign, an echocardiographic finding of segmental right ventricular wall‐motion abnormality with apical sparing, is highly specific and may guide therapeutic intervention. We present the case of a 59‐year‐old man who was found to have acute pulmonary embolism with obstructive shock, managed successfully with thrombolytic therapy ...

McConnell’s sign is a well-established, specific echocardiographic sign for acute pulmonary embolism. Multiple theories have been proposed regarding the mechanism of McConnell’s sign in the context of acute pulmonary embolism. Here, we present 2 ...

McConnell's sign is the most distinct echocardiographic finding described in patients with APE.1 There is a regional pattern of right ventricular dysfunction, with akinesia of the mid free wall and hyper contractility of the apical wall.1 McConnell's sign is considered as a specific sign of APE.2 Though echocardiography has poor sensitivity, ...

Although occasionally encountered in clinical practice, published cases of McConnell’s sign related to right ventricular ischemia are limited. 5-8 McConnell’s sign has long been established as an echocardiographic sign with high specificity for acute PE. 1 A recent meta-analysis in patients with suspected PE confirmed that McConnell’s ...

McConnell’s sign sensitivity and specificity were described in many observational studies. It was shown to be highly specific for the acuity of PE, especially in critical care settings, however it lacks sensitivity. 6 12 In summary, McConnell’s sign is a typical echocardiographic and useful sign of …

"McConnell's sign", defined as RV free wall hypokinesis in the presence of normal RV apical contractility, has 77% sensitivity and 94% specificity for the diagnosis of acute pulmonary embolism, with a positive predictive value of 71% and a negative predictive value of 96% (8). Casazza et al., however, demonstrated that McConnell's sign can also ...

McConnell’s Sign or Acute regional RV Dysfunction. McConnell’s sign is one of the most distinct echocardiographic findings in patients with acute pulmonary embolism. The sudden pressure overload on the RV also causes increased wall stress. As a result, it is left mechanically stunned.