The signs and symptoms of Leigh syndrome are caused in part by patches of damaged tissue (lesions) that develop in the brains of people with this condition. A medical procedure called …

Leigh syndrome is a rare, complex, and incurable early onset (typically infant or early childhood) mitochondrial disorder with both phenotypic and genetic heterogeneity.

Who is at risk for Leigh Syndrome, French Canadian Type? LSFC is most common in individuals of French Canadian ancestry, specifically those from the Saguenay-Lac-Saint-Jean (SLSJ) …

Leigh syndrome is an incredibly rare disorder that has major effects on those affected and often manifests in infancy or early childhood. It is characterized by things like vomiting, feeding …

Leigh syndrome is the most common pediatric presentation of mitochondrial disease. This neurodegenerative disor-der is genetically heterogeneous, and to date pathogenic mutations …

•Postmortem examination demonstrated bilateral symmetric necrotic lesions in the brain and spinal cord •The condition he described became known as “Leigh’s disease” and ultimately …

BACKGROUND AND PURPOSE: Subacute necrotizing encephalomyelopathy, or Leigh syn- drome (LS), is a progressive neurodegenerative disorder characterized by symmetrical spon- …