As biomarker testing becomes more common in Alzheimer’s research, scientists face the tricky question of whether to disclose results. In studies of hypothetical scenarios, including a recent survey ...

What are physicians learning from their early experiences prescribing amyloid immunotherapy? In the May 12 JAMA Neurology, Joy Snider and Suzanne Schindler and colleagues at Washington University, St.

Nominations for the 2026 Rainwater Prizes are being solicited via peer- and self-nominations. The Rainwater Prize recognizes outstanding scientists who have either made significant discoveries or who ...

The brains of α-synuclein KO mice appear largely normal. No significant differences were observed with unbiased stereology in the number of tyrosine hydroxylase–positive neurons in the midbrain ...

Tau pulls the plug on the neural activity that forms memories, according to researchers led by Marc Aurel Busche at the U.K. Dementia Research Institute at University College London. On April 23 in ...

Clusterin, we’re sorry—we misjudged you. Long cast as Aβ’s villainous sidekick (Jan 2014 news; Apr 2023 news), the chaperone now looks more like a friendly superhero. Provided, that is, our genes let ...

Jeff Oslund, M.A. in geology, B.A. in chemsitry Houston, United States ...

To mark the 20th anniversary of Alzforum's launch in 1996, we have compiled a timeline reflecting the evolution of Alzheimer’s disease research, starting from Alois Alzheimer's public presentation of ...

Converging evidence suggests that hearing loss during midlife increases a person’s odds of getting dementia. Now, research from Johns Hopkins’ Bloomberg School of Public Health, Baltimore, suggests ...

At the AD/PD meeting held last month in Vienna, scientists implicated T lymphocytes—specifically, the cytotoxic, CD8-positive variety—in Alzheimer’s disease. While the modus operandi of these cells in ...

Cells, are you experiencing stress? Quick, SUMOylate your TDP-43 before it’s too late! Three independent papers appearing in rapid succession deliver the same message: Chain the small ubiquitin-like ...

Because hypertension is linked to a greater risk of dementia, several trials have investigated whether lowering blood pressure in older people would protect the brain. Data from cohorts of a few ...