In the majority of cases of motor neuron disease (MND), diagnosis is clinical and unambiguous. However, given the gravity of the diagnosis, it is crucial that treatable mimics are differentiated ...

Pancreatic cancer is a malignancy with poor prognosis and overall poor response to systemic therapy. Moreover, patients with locally advanced or unresectable tumours have historically worse outcomes ...

Akathisia is a subjective feeling of restlessness that often results in a compulsion to move. Drug-related causes are the most common aetiologies. It can often be confused with restless legs syndrome ...

Necrotising enterocolitis (NEC) is a life-threatening condition predominantly affecting preterm neonates. In contrast to well-characterised neonatal forms, adult NEC (ANEC) is a rare entity. Early ...

A woman in her mid-50s contacted her social worker and expressed intent to commit suicide by ingesting prescription medications. On arrival of emergency responders, the patient was found unconscious ...

A 35-year-old male patient, tracheostomised for about 10 years, presented to our hospital with a dyspnoea of 2 days duration. There was a history of accidental decannulation of the tracheostomy tube ...

Susac's syndrome is a microangiopathy of the retina, inner ear and brain manifesting as a triad of encephalopathy, hearing loss and branch retinal artery occlusion. The pathological mechanism is ...

We present the case of a 17-year-old male with a sore throat, tender cervical lymphadenopathy, bilateral erythematous and enlarged tonsils, fever, joint pain, widespread tender purpuric nodules, ...

Denosumab is a fully human antibody to receptor activator of nuclear factor kappa-B ligand (RANKL), and it is administered every 6 months in women with postmenopausal osteoporosis (PMO) at high risk ...

2 Department of Otolaryngology and Head and Neck Surgery Service, Reina Sofia Hospital, Córdoba, Spain We present a case of a 67-year-old man who was an active smoker, with a clinical history of ...

Bing-Neel syndrome (BNS) is a very rare manifestation of Waldenström macroglobulinaemia (WM), in which lymphoplasmacytic cells invade the central nervous system. The clinical presentation includes ...

Neuroleptic malignant syndrome (NMS) is an uncommon but serious adverse effect that is mainly associated with antipsychotics. NMS induced by donepezil, an acetylcholine esterase inhibitor, has been ...