Jurickson Profar, coming off a one-hit performance in his previous game (1-for-4), will take the field for the San Diego ...

Everything you need to know about the San Diego Padres vs. Chicago White Sox game on Sept. 22, including how to watch info, ...

Manny Machado’s San Diego Padres play the Chicago White Sox on Sept. 21 at 8:40 PM ET, and will see starting pitcher Chris ...

The Chicago White Sox (36-117) begin a three-game series against the San Diego Padres (87-66) on Friday at PETCO Park. First ...

The Houston Astros (82-69) and San Diego Padres (86-66) meet Wednesday for the finale of a 3-game series. First pitch from ...

When he approached the umpires to explain that, they confirmed that the ball was fair. Astros manager Joe Espada came out of ...

Following a stretch of four consecutive wins, the San Diego Padres (86-65) meet the Houston Astros (81-69) at 9:40 p.m. ET on ...

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Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

The San Diego Padres (88-66) will host the Chicago White Sox (36-118), Saturday at 8:40 p.m. ET, with the White Sox on a ...

Analyzing Friday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

Preview the Padres vs. White Sox game today, with score predictions, stats, starting pitchers and game information.