The 49ers revealed their status reports Friday for their injured players ahead of Sunday’s visit to the Los Angeles Rams.

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

Just as the San Francisco 49ers won’t miss seeing Aaron Donald lining up for the Los Angeles Rams on Sunday, Sean McVay won’t ...

ESPN sources: 49ers officially are placing All-Pro RB Christian McCaffrey on injured reserve due to his calf tightness and ...

The San Francisco 49ers have placed All-Pro running back Christian McCaffrey on injured reserve because of his lingering calf ...

The San Francisco 49ers placed star running back Christian McCaffrey on injured reserve, further supporting the claim that ...

There are plenty of questions swirling around with the San Francisco 49ers right now with Christian McCaffrey on the Injured ...

San Francisco 49ers running back Christian McCaffrey will be eligible off the injured reserve after Week 6, but could still miss a pivotal Week 7 Super Bowl rematch with the Kansas City Chiefs.

"Nobody knows" when Christian McCaffrey will be ready to return from injured reserve, 49ers coach Kyle Shanahan said Sunday.

The star running back missed the team's season-opening win over the New York Jets as he battles calf and Achilles injuries.

San Francisco 49ers running back Christian McCaffrey is out for at least the next four games; Watch the San Francisco 49ers ...

Christian McCaffrey's stint on the IR might go further than four weeks but the San Francisco 49ers running back could explore ...