Background: Infertility poses a substantial societal and economic burden; however, current preventive strategies are limited. Recently, the relationship between gut microbiota and infertility has ...

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One of the key underlying mechanisms of NAFLD, in which the body needs more insulin to maintain regular metabolic processes, is insulin resistance (IR). IR is significantly influenced by lipotoxicity ...

Background The study of endogenous insulin secretion may provide relevant insight into the comparison of the natural history of adult onset latent autoimmune diabetes (LADA) with types 1 and 2 ...

This mimicking action results in glucose-dependent insulin secretion, lessening glucagon secretion (the hormone that stimulates glucose production) and slowing food movement through the stomach, known ...

Insulin is a hormone made in your pancreas, a gland located behind the stomach. It allows your body to use glucose for energy. Glucose is a type of sugar found in many carbohydrates. The body ...

This secretion and delivery mechanism is instrumental in processes such as tumor stroma recruitment, invasiveness, and metastasis. Despite the promising applications of miRNAs in diagnostics, ...

Figure 2: Biochemical mechanisms of glucose-stimulated insulin secretion, including roles of the pyrvuate cycling pathways of the β-cell. The recent studies summarized in this article have ...

The present study shows that the stimulated insulin secretion capacity in LADA is intermediate between that of types 1 and 2 diabetes. This finding provides new data and further contributes to the ...