Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...

A pioneering research study details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the brain to ...

In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment ...

The human gut is home to trillions of microbes that not only aid in digestion, but also play a key role in shaping our immune ...

Researchers at the Tohoku University Graduate School of Medicine have uncovered a key primary step in the hepatic ERK pathway ...

BACKGROUND: Exercise improves functional outcomes in patients with diabetic cardiomyopathy (DiaCM). The molecular mechanism underlying cardiac benefits of exercise in DiaCM remains incompletely ...

Study in mice shows how a host-elicited factor benefits gut immunological homeostasis by selectively targeting commensal ceramide molecules.

Growth factor signalling is a cell signalling pathway that regulates the growth and development of an organism. Secreted growth factors bind to transmembrane growth factor receptors to stimulate ...