BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...

A research team at the University of Cologne discovered that the 1N4R tau protein isoform plays a key role in Alzheimer’s disease by mediating the toxic effects of protein clumps in brain cells. Using ...

"The preliminary results of that study, which is a phase 1/2 dose escalation and dose expansion trial, were presented by Professor Ben Tran last year at the ENA meeting1 and showed a very favorable ...

Version of Record: This is the final version of the article. This study investigated the role of PLECTIN, a cytoskeletal crosslinker protein, in liver cancer formation and progression. Using the liver ...

This is due to their lack of affinity for HSPG (16). The FGFR family comprises four members, FGFR1-4, which are highly conserved tyrosine kinase transmembrane receptors (RTKs). Additionally, there is ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

1 Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Department of Basic Medicine, Gannan Medical University, Ganzhou, China 2 Department ...

Medicinal Chemistry Research Group and National Drug Discovery and Development Laboratory, HUN-REN Research Centre for Natural Sciences, 2 Magyar tudósok krt, Budapest 1117, Hungary ...