Overview: Transdermal estradiol is available as a patch, gel, or spray that is applied to the skin to increase estrogen levels. It is used after menopause to prevent osteoporosis or to reduce ...
during the screening period were randomised to receive either oral CEE 0.3 mg/day or an estradiol patch delivering 0.025 mg/day for 12 weeks. Patients were assessed after three 28-day cycles.