Valganciclovir currently is approved by FDA for the treatment of active CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for the prevention of CMV disease in kidney ...

Discover surprising truths about blindness, from the spectrum of visual impairment to revolutionary treatments and adaptive ...

This paper reports a clinical case of retinitis due to congenital CMV infection in a preterm infant and reviews the relevant literature. Case presentation: A 2-day-old female infant at 36 +2 gestation ...

Suzanne M Mitchell, St Stephen’s Centre, Chelsea and Westminster Hospital, Fulham Road, London SW10 9NH. AIMS To report a series of patients requiring treatment for falling visual acuity associated ...

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa. No therapy exists for this rare inherited disease ...

Drugs used for CMV prophylaxis in patients with solid organ transplants include CMV immune globulin i.v., acyclovir, valacyclovir, ganciclovir, and valganciclovir. The mechanisms of action and ...

At age 28, during an ophthalmologist appointment to seek reading glasses, Luehrs was diagnosed with retinitis pigmentosa, a progressive, inherited eye disease of the retina. "His words were ...

The researchers conducted proof-of-concept experiments in human cells and a mouse model of retinitis pigmentosa, finding that the bespoke enzymes had greater specificity. "A major outcome of this ...

Nanoscope Therapeutics is on the brink of filing for FDA approval of what could be the first gene therapy for incurable eye disease retinitis pigmentosa (RP) that can be used regardless of ...

For individuals with inherited eye disorders such as retinitis pigmentosa or macular degeneration, the irreversible degeneration of the retina—a layer of photoreceptors at the back of the eye—can ...