The Detroit Lions are missing several key players entering their Week 17 game against the San Francisco 49ers, but there is a ...

Kickoff between the San Francisco 49ers and Detroit Lions is just hours away. Ahead of their Week 18 matchup at Levi's ...

Detroit Lions and San Francisco 49ers meet on Monday Night Football in NFL Week 17. Find live updates, score summary, game ...

The Lions have already defeated the Vikings once this season at U.S. Bank Stadium. If Detroit wins again, they're in based on ...

After building a 17-point halftime lead, the Lions were unable to finish the game and the San Francisco 49ers rallied to ...

Check out these five of the best anytime TD prop bets for this NFL matchup between the 49ers and Lions on MNF. Find key stats ...

The Lions travel to Santa Clara to battle the 49ers on Monday Night Football. The 49ers-Lions game starts at 8:15 p.m. ET on ...

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The Lions (13-2) are looking to continue their winning ways against the 49ers (6-9) and keep their spot at the top of the NFC ...

The Week 17 edition of Monday Night Football may not mean much for either the San Francisco 49ers or Detroit Lions, but it means plenty for bettors and fantasy ...

BetMGM Bonus Code 'CUSE50' unlocks $100 in bonuses or $1,500 first bet insurance for Lions vs. 49ers on Monday Night Football ...

Jefferson will join Craig Reynolds and rookie Sione Vaki in adding depth behind workhorse Jahmyr Gibbs. David Montgomery remains out with a knee injury. Montgomery has not been placed on injured ...