Once a drug target is identified, it often takes decades until a chemical compound is developed that can hit the bullseye and ...

The awards were made possible by ongoing support from the Blavatnik Family Foundation that aims to spur scientific ...

Immunotherapy has redefined cancer treatment, but not all patients experience the same benefit when treated. New research in mice identifies how gut bacteria alter the body’s response to a common form ...

A protein called STUB1 weakens the cancer-killing power of immune T cells by blocking key signals they need to attack tumors. Disabling STUB1 in lab experiments strengthened T cells’ response to the ...

If current guidelines for cholesterol and high blood pressure treatment remain unchanged, a newly unveiled heart risk calculator would render 16 million people ineligible for preventive therapy. Loss ...

“Dr. CaBot” goes head-to-head with a human expert to work through a challenging medical case ...

Three key players share the story of how fundamental discoveries in the laboratory became a first-of-its-kind therapy that promises to have a monumental impact on sickle cell disease patients around ...

This article is part of Harvard Medical School’s continuing coverage of COVID-19. A new study of more than 800,000 people has found that in the U.S., COVID “long haulers” were more likely to be older ...

Sleep is one of the most essential human activities — so essential, in fact, that if we don’t get enough sleep for even one night, we may struggle to think, react, and otherwise make it through the ...

Love has been the source of ceaseless fascination since antiquity. Artists have tried to capture its beauty and darkness in books, paintings, and songs. Behavioral scientists have explored love as a ...

Charles R. Broderick, an alumnus of Harvard University and MIT, has made gifts to both alma maters to support fundamental research into the effects of cannabis on the brain and behavior. The total ...

Top row: In a mouse model of Alzheimer's disease, lithium deficiency (right) dramatically increased amyloid beta deposits in the brain compared with mice that had normal physiological levels of ...