During cell division, adherent animal cells round up to create the precise spatial geometry required for accurate chromosome ...

The membrane that encases a biological cell is not simply a barrier; it is chock full of proteins involved in all sorts of critical biological functions. To really understand what membrane proteins ...

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most ...

Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Scientists have discovered how the amino acid leucine boosts the body’s energy production by protecting key mitochondrial ...

Researchers have identified the drivers of an extracellular protein degradation pathway, which could be the key to a new generation of therapeutics. In a recent study, chemists at Stanford University ...

G protein-coupled receptors (GPCR) are a large and diverse class of plasma membrane receptors involved in transduction of extracellular signals. The range of GPCR ligands is broad and includes small ...

There are many kinds of T cells, and they play different parts in defending the body. Some T cells kill infected cells, ...