Researchers performed a cross-sectional study involving 1,151 participants from the ages of 6 to 18. New research uncovers ...
By knocking out TEFM, they observed a notable reduction in mtDNA copy number, alongside a decrease in 7S DNA levels and strand-asynchronous replication intermediates. These findings suggest that ...
Somatic point mutations in mitochondrial DNA (mtDNA) have been linked to aging and cancer. Each cell contains a large number of mtDNA molecules, so any mutation requires a process of clonal expansion ...