NFL Week 18 odds, picks, predictions, TV channel, streaming information for Sunday football game between San Francisco 49ers and Arizona Cardinals.

The Arizona Cardinals know the date and time for their season finale against the San Francisco 49ers. The NFL announced its Week 18 schedule and, as was expected, the Cardinals and 49ers will play in the Sunday late afternoon slot.

With the help of three other teams, the Los Angeles Rams clinched the NFC West on Sunday after beating the Arizona Cardinals the night prior. In doing so, they secured either the No. 3 or 4 seed in the playoffs.

Sunday's regular-season finale between the Seattle Seahawks and Los Angeles Rams looked like it could be a de facto NFC West championship game for a while, but sadly, it will not be. The Rams' 13-9 win over the Arizona Cardinals put them on the verge of clinching the NFC West and thus eliminating the Seahawks.

They’ve been crowned NFC West champions with one week still to go, a home matchup with the Seattle Seahawks. According to BetMGM, the Rams are 2.5-point underdogs in that game, which seems like an odd line on the surface.