No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

Monoclonal antibodies (mAbs) are nature's biological ... again until 1992–1994 (Table 1). During that period, a larger number of humanized mAbs began entering clinical studies.

In 1975, Georges Köhler and César Milstein, biochemists from the Medical Research Council Laboratory of Molecular Biology, published a paper in Nature about a hybridoma technology that enabled the ...

There are various FDA-approved indications of monoclonal antibodies (see table below). 3 Common indications include the following. Cancer treatment: anticancer immunotherapy against prostate, breast, ...

Antibodies bind to specific antigens on pathogens. This means that only one type of antibody will bind to a matching antigen. For example, an antibody that can recognise an antigen on the ...

The FDA is moving away from requiring animal models for investigational new drug (IND) applications for new monoclonal ...

Antibodies bind to specific antigens on pathogens. This means that only one type of antibody will bind to a matching antigen. Scientists discovered that we could make antibodies to bind to ...