Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team ... Parking a giant CRISPR repressor on DNA is helpful for ...

If DNA is a book, then how is it read ... for hundreds or even thousands of nucleotides beyond the end of a noncoding sequence. The RNA strand is then cleaved by a complex that appears to ...

Professor and HHMI Investigator Zachary Lippman and his colleagues have begun to uncover the ways in which fragments of ...

Evo 2 used DNA sequences alone. With further validation, the tool could one day help scientists find the genetic causes of diseases—especially those hidden in non-coding regions. It could also aid new ...

Long noncoding RNAs (lncRNAs) are RNAs longer than 200 nucleotides that do not contain any open reading frames greater than 300 nucleotides (100 codons). The DNA sequences they’re transcribed from can ...

Swiss start-up Haya Therapeutics has formed a partnership with Eli Lilly – worth up to $1 billion – to look for new therapies for obesity in non-coding DNA. The biotech focuses on trawling the ...