Organic chemistry students and bench chemists alike rely on the Grignard reaction, a relatively simple way to make carbon-carbon bonds. But even though the reaction was first described 120 years ago, ...

Session 1: Making Grignard reagents and safety aspects of making and handling Grignard reagents. This presentation will cover the main ways for preparing organomagnesium compounds, and consider their ...

Making complicated organic molecules is like solving a Rubik’s cube. Organic chemists need to design sequences of reactions to carefully build up parts of a molecule, while maintaining the structure ...

The Grignard reaction is a powerful, frequently used organometallic transformation to add important structural motifs to carbonyl compounds resulting in secondary or tertiary alcohols. Since usually ...