With the help of zinc reagents, chemists have found a loophole in rules that govern additions to chiral carbonyl compounds, a fundamental reaction in organic synthesis. The work, presented on March 24 ...

Products of unfavorable chemical equilibria are not readily observed because their high energy and increased reactivity result in low concentrations. Biological macromolecules use binding forces to ...

Reactions that form carbon-carbon bonds hold a place of special importance in chemical synthesis. Researchers who excel in this field develop a knack for applying these reactions masterfully and use ...

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...

In this review, our recent results on the concurrent cationic vinyl-addition and ring-opening copolymerization of vinyl ethers (VEs) and oxiranes are summarized, with particular emphasis on the ...

Science, founded by Thomas A. Edison in 1880 and published by AAAS, today ranks as the world's largest circulation general science journal. Published 51 times a year, Science is renowned for its ...