Candesartan cilexetil was administered once daily, starting at 4mg with up-titration biweekly to 8mg and 16mg, respectively. Trough plasma concentrations of candesartan were determined before ...

Patients and Methods: After a 2-week placebo washout period, 326 patients with essential hypertension were randomised to receive amlodipine 5mg once daily or candesartan cilexetil 8mg once daily ...