1. Röhrig B, du Prel JB, Blettner M: Study design in medical research – Part 2 of a series on evaluation of scientific publications [Studiendesign in der medizinischen Forschung. Teil 2 der Serie zur ...

The selection of suitable outcomes and sample size calculation are critical factors in the design of a randomised controlled trial (RCT). The goal of this study was to identify the range of outcomes ...

Choosing the proper sample size for an investigation is one of the crucial jobs required of a statistician. Regardless of whether the statistician is deciding the number of patients to select in a ...

In epidemiologic studies and disease prevention trials, interest often involves estimation of the relationship between some disease endpoints and individual exposure. In some studies, due to the ...

For a desired power of detecting the association between a disease and several potential risk factors in case-control studies, Yang (1978, Biometrika 65, 635-640) and Halperin (1980, Biometrika 67, ...