Melanoma is a type of skin cancer that starts when pigment cells in the skin grow uncontrollably, rising for the last 30 ...

Vemurafenib (ZELBORAF, Hoffmann-La Roche Inc; Figure 1) is a first-in-class selective inhibitor of the BRAF serine-threonine kinase, FDA approved for the treatment of metastatic melanoma harboring ...

Pfizer Inc. (NYSE: PFE) today announced longer-term follow-up results from the Phase 2 single-arm PHAROS clinical trial evaluating the efficacy and ...

We played a major role in characterising the BRAF gene and its role in cancer, increasing our understanding of malignant melanoma. Our work on the gene ... selective BRAF inhibitors developed another ...

A new research perspective titled "Targeting the multifaceted BRAF in cancer: New directions" has been published in ...

The study will also evaluate the effect of the combination on tumor biomarkers, safety and anti-cancer activity in patients with BRAFV600 wild type melanoma ... melanoma with BRAF V600E or ...

The presence of mutated BRAF in such a high proportion of melanoma cases and in such a wide range of human cancers, led researchers to examine the protein as a target for anticancer therapy. A team ...

The more serious type, melanoma, has long been enemy number one. But European dermatologists have now found less deadly varieties of skin cancers are now driving the majority of deaths.

NEW YORK, Sept 14 (Reuters) - Pfizer (PFE.N), opens new tab is trying to increase doctor awareness of and testing for a rare lung cancer mutation to help boost use of its drug Braftovi, which the ...

LAist Studios present Passing The Mantle: Is Gen Z less curious than the Baby Boomers? July 8, 2024 • Passing the Mantle is a new podcast from LAist Studios about family, curiosity and the ...

Melanoma is the most serious type of skin cancer. It develops when skin cells multiply rapidly as a consequence of mutations in their DNA caused by UV exposure. Melanomas originate in the pigment ...

Thank you. THE WILD is a production of KUOW, Chris Morgan Wildlife, and the NPR Network. This episode was produced by Matt Martin and edited by Jim Gates. The Wild is hosted, produced and written ...