Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

Follow along with live updates as the San Francisco 49ers begin a crucial four-game stretch starting in Arizona against the Cardinals.

The Arizona Cardinals set a new franchise record during a loss to the San Francisco 49ers on Sunday, but not the good kind.

Arizona Cardinals running back Emari Demercado is dealing with an ankle injury in the first half of the Week 11 game against ...

Bam Knight is active for the Arizona Cardinals' Week 11 game against the San Francisco 49ers and will likely lead the ...

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch ...

Cardinals' QB Jacoby Brissett completed more passes today than anyone in NFL history originally appeared on The Sporting News ...

The Arizona Cardinals and San Francisco 49ers revealed their final inactives report for Week 11 - who's in, who's out?

San Francisco 49ers wide receiver Skyy Moore opens the game against the Arizona Cardinals with a 98-yard kick return.