In a recent study of patients with acute gout, oral prednisolone was as effective ... to receive either oral prednisolone (35 mg daily) or naproxen (500 mg twice daily) for 5 days.

The first gout attack typically affects the big toe ... Over-the-counter NSAIDs typically include Motrin or Advil (ibuprofen) and Aleve (naproxen). However, NSAIDs aren't right for everyone.