Nuclear genes and OXPHOS With only 13 OXPHOS polypeptides encoded by mtDNA, the bulk (at least 70) of the OXPHOS subunits are encoded by the nuclear genome. There are also several nuclear gene ...

A new study by the group has identified 13 genes, termed "high probability risk genes," that directly contribute to joint tissue loss and greatly increase a person's chances of developing ...

Human mitochondrial DNA (mtDNA) encodes only 13 proteins — the rest (roughly 99%) are encoded by nuclear genes and imported into mitochondria 3. These organelles normally work in tandem with the ...

Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ...

At the top of the inverted tree is mitochondrial "Eve"; the illustration shows two mtDNA sub-branches, or lineages, found in Europe and the Middle East. The J1- and J2-branch polymorphisms in the ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.