Christian McCaffrey's injury woes tripped up the San Francisco 49ers last season. Can they overcome any absence from him this year?

Guerendo is hoping to carve out a bigger role in the offense after averaging five yards per carry last season, albeit on just 84 carries. His size and speed give him big-play potential, and Kyle Shanahan has a history of scheming up explosive runs. With Jordan Mason gone, does Guerendo step into his own role, or is he simply McCaffrey’s backup?

The sting of a disappointing 2024 season still lingers in the San Francisco 49ers locker room. Once projected as Super Bowl contenders, the team fell far short of expectations, finishing with a 6-11 record in a season plagued by injuries.