In just under 24 hours the biggest game of the NFL season will take place in Detroit as the Lions host the Minnesota Vikings ...

Jared Goff threw three touchdown passes and the Detroit Lions tuned up for their Week 18 division showdown against Minnesota ...

SportsLine's model has simulated San Francisco vs. Detroit on Monday Night Football 10,000 times and revealed its MNF picks ...

In the final game of Week 17, the San Francisco 49ers will play host to the Detroit Lions on "Monday Night Football." San ...

For the seventh time this season, the NFL has fined Detroit Lions safety Brian Branch $10,128.

The Detroit Lions continue to set franchise and league marks across the board. Their latest re-writing of the NFL history ...

With the high-scoring contest against the 49ers, the Lions clinched their fifth game this season with 40 points and 0 ...

SportsLine expert Jimmie Kaylor shares his Week 17 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool ...

The 49ers have nothing to play for other than pride at this point. They're facing a Lions team that has the best record in ...

The NFL Week 17 schedule concludes with a pair of high-profile NFC teams on Monday Night Football. The Detroit Lions at San ...

In other words, the 49ers’ disappointment is getting worse as the season carries on. San Francisco has already lost stars in ...

Lions vs. 49ers predictions and expert picks for Monday Night Football on December 30. Expect a big night from Jauan Jennings ...