Four quarterfinal matches will be contested on Friday at the ATP Brisbane International, with two top 10 players and some young stars all vying for a semifinal spot.

As Novak Djokovic ascended to the pinnacle of tennis history, Reilly Opelka was watching from the sidelines, using Djokovic's success to plot his own return from injury, culminating in a stunning boilover victory at the Brisbane International.

Novak Djokovic, seeking to become just the third player to win 100 ATP Tour titles, advanced to the Brisbane International quarterfinals with a victory vs. Gael Monfils.

Reilly Opelka secured the biggest win of his comeback over Novak Djokovic in the Brisbane International quarterfinals.

Novak Djokovic's quest for his 100th ATP title ends with a quarter-final loss to Reilly Opelka at the Brisbane International. Aryna Sabalenka advances in the women's event, while Naomi Osaka reaches her first semi-final in three years at the Auckland Classic.

Top seed Novak Djokovic is out of the Brisbane International, beaten 7-6 (8-6) 6-3 in the quarter-finals by Reilly Opelka.

Get the live streaming details, head-to-head, and preview of the Novak Djokovic vs Reilly Opelka, quarter-final match at the Brisbane International 2025 right here

Novak Djokovic's hunt for a landmark 100th ATP title ended with a whimper following an unexpected 7-6(6) 6-3 defeat by big-serving American Reilly Opelka in the Brisbane International quarter-finals on Friday.

Djokovic is in search of his 25th Grand Slam title at the Australian Open, but fell short of the semifinals at his warm-up event.