Great Mills is an unincorporated community in St. Mary's County, Maryland, United States. Great Mills High School serves the lower end of the county, including the town of Lexington Park. The area is site of some of the oldest agricultural settlements in Maryland, as well as English speaking North America. It had many links to the original Maryland c…Great Mills is an unincorporated community in St. Mary's County, Maryland, United States. Great Mills High School serves the lower end of the county, including the town of Lexington Park. The area is site of some of the oldest agricultural settlements in Maryland, as well as English speaking North America. It had many links to the original Maryland colony in St. Mary's City.